Theracurmin HP

BIOLOGICAL EFFECTS OF CURCUMIN
For over more than three decades, in vitro and in vivo research demonstrates that curcumin supports detoxification and cytokine pathways.*6,7 While mechanisms of action are still under investigation, the chemical structure of curcumin directly influences antioxidant pathways, with its phenolic hydroxyl group behaving as an electron donor.7 Based on in vitro and in vivo studies, curcumin's indirect effects on antioxidant pathways include modulating cellular redox homeostasis and enhancing the activity of antioxidant enzymes like catalase, superoxide dismutase, glutathione peroxidase and glutathione-S-transferase, enzymes that also support detoxification and cytokine pathways.

REFERENCES
Sasaki H et al. Biol Pharm Bull. 2011;34(5):660-5.
Sunagawa Y et al. J Nutr Sci Vitaminol. 2015;61:37-44.
Akazawa N et al. Nutr Res. 2012;32(10):797-9.
Tanabe Y et al. Eur J Appl Physiol. 2015;115(9):1949-57.
Nakagawa Y et al. J Orthop Sci. 2014;19:933-9.
Gupta SC et al. Clin Exp Pharmacol Physiol. 2012;39(3):283-99.
Xu XY et al. Nutrients. 2018;10:1553.

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